DNA modification methyltransferase
- DNA modification methyltransferase
Модификационная метилаза, ДНК-модификационная метилтрансфераза — бактериальный фермент, катализирующий перенос метильных групп с S-аденозил-L-метионина на определенные основания в ДНК. Поскольку метилирование таких оснований в сайте узнавания рестриктазой предотвращает процесс узнавания и, следовательно, разрыв ДНК в этом месте, то метилирование защищает бактериальную ДНК от собственного и чужеродного фермента рестрикции. М. м. с высокой специфичностью к определенным последовательностям, узнаваемым эндонуклеазами, используются также для защиты сайтов рестрикции в клонируемых фрагментах ДНК.
Англо-русский толковый словарь генетических терминов. — М.: Изд-во ВНИРО.
Арефьев В.А., Лисовенко Л.А., науч. ред. Л.И.Патрушев.
1995.
Смотреть что такое "DNA modification methyltransferase" в других словарях:
DNA methyltransferase — N 6 DNA Methylase crystal structure of type i restriction enzyme ecoki m protein (ec 2.1.1.72) (m.ecoki) Identifiers Symbol N6 Mtase Pfam … Wikipedia
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Methyltransferase — HaeIII methyltransferase / DNA. Rendered from PDB 1DCT … Wikipedia
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Protein-glutamate O-methyltransferase — Identifiers EC number 2.1.1.80 CAS number 9055 09 8 … Wikipedia
Restriction modification system — The restriction modification system (RM system) is used by bacteria, and perhaps other prokaryotic organisms to protect themselves from foreign DNA, such as bacteriophages. This phenomenon was first noticed in the 1950s. Certain bacteria strains… … Wikipedia
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DNMT1 — DNA (cytosine 5 ) methyltransferase 1 Identifiers Symbols DNMT1; AIM; CXXC9; DNMT; FLJ16293; MCMT; MGC104992 External IDs … Wikipedia
DNMT3L — DNA (cytosine 5 ) methyltransferase 3 like Rendering based on PDB 2PV0 … Wikipedia
Epigenetics — In biology, the term epigenetics refers to changes in gene expression caused by mechanisms other than changes in the underlying DNA sequence. These changes may remain through cell divisions for the remainder of the cell s life and may also last… … Wikipedia
Restriction enzyme — Glossary Restriction … Wikipedia
